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However, efforts must also focus on the interim strategy to slow neuron losses in brain structures impacted including neocortices, hippocampus, locus ceruleus and the nucleus basalis of Meynert by stimulating synaptogenesis, neurogenesis and reducing neuroinflammation and oxidative stress

Study of Heart and Renal Protection (SHARP): randomized trial to assess the effects of lowering low-density lipoprotein cholesterol among 9,438 patients with chronic kidney disease

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Akkermansia muciniphila and Faecali prausnitzii protect against the pathogenesis of T2DM by maintaining the integrity of mucin layer and reducing inflammation (160, 161)

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