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It can subtly lighten the skins pigmentation by inhibiting melanin production, leading to a more even skin tone and glow. \ Moreover, as a potent antioxidant, glutathione helps minimize oxidative damage in the skin that contributes to wrinkles, fine lines, and dull complexion

In IESS patients, ACTH treatment decreases Lachnospiraceae incertae sedis abundances while increasing Alistipes and Rikenellaceae abundances [283]

p53 induction by tumor necrosis factor-alpha and involvement of p53 in cell death of human oligodendrocytes