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Bioscience of Microbiota, Food and Health

237,238 Several studies using animal models have demonstrated that acute GLP-1 infusion increased heart rate, blood pressure and glucose uptake by the heart, whereas chronic GLP-1R agonism in rodents reduced blood pressure and prevented hypertension

Consumption of an unhealthy diet, excessive alcohol use, smoking, and lack of physical activity are considered traditional health risk factors for CVD 3

Dula is a long-acting GLP-1 RA with 90% human homology that was approved by the US FDA in 2014 (half-life: 5 days)

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Dysautonomia, particularly Postural Orthostatic Tachycardia Syndrome (POTS), frequently co-occurs with Long COVID and ME/CFS