Walsh and colleagues suggested that human plasma contains pro-survival factors as it has the capacity to inhibit erythrocytic PS exposure induced by the apoptosis inducer BH3-mimetics ( The Dynamics of PS Exposure Over Time Although induction of PS exposure in nucleated cells occurs in a matter of minutes ( Eryptosis Inducers Do Not Induce Eryptosis of Nave or Plasmodium -Infected Erythrocytes We selected six eryptosis inducers (amiodarone, BAY 43-9006, cordycepin, oridonin, benzethonium, apigenin) based on their use (or prospective use) in the clinic, their known molecular targets and/or their previously demonstrated antimalarial effects
The role of oxidative stress in viral infections
The effects are sustained, lasting at least six days in healthy adults
b , Representative bright field images of Huh7 cells treated with vehicle and indicated inhibitors for 72 h
Data availability The dataset generated during and/or analyzed during the current study will be available from the corresponding author (MM) upon reasonable request and once the dataset has been fully exploited by the authors
Sanjari M, Yarmohammadi H, Fahimfar N, et al