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For recycling, cells were incubated with agonists at 37 C for 15 min, followed by endocytosis arrest at 4 C, surface label removal as above, 30 min incubation at 37 C with 10 M exendin(9-39) to prevent further internalization, and a second round of surface label removal at 4 C

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Peripheral or central GLP-1 suppresses food intake and reduces body weight

While these medications support weight loss, loss of muscle mass can occur in the short term if physical activity is not included

Its stability and consistent angiogenic signal make it a common pairing with TB-500

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