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doi: 10.14348/molcells.2015.0258 11 WangQZhangHXuHGuoDShiHLiYet al

Why it matters: During moderate-to-severe dehydration, plasma volume contracts, reducing cardiac output and oxygen delivery to tissues

4 About the Compound Dihexa is a small synthetic oligopeptide derived from the three N-terminal residues of angiotensin IV (Nle-Tyr-Ile), with structural modifications that block enzymatic degradation, increase lipophilicity, and confer oral bioavailability and blood-brain barrier permeability