If I'm plateauing on semaglutide, should I add tirzepatide or switch medications
[1] While the term "bloating" specifically is not listed in the FDA prescribing information, related gastrointestinal symptoms such as abdominal distension and dyspepsia are among the commonly reported side effects with tirzepatide therapy
Semaglutide (Wegovy) : Similar to liraglutide, this GLP-1 agonist may also elevate heart rate modestly
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Baez-Duarte BG, Mendoza-Carrera F, Garcia-Zapien A, Flores-Martinez SE, Sanchez-Corona J, Zamora-Ginez I, Torres-Rasgado E, Leon-Chavez BA, Perez-Fuentes R, Multidisciplinary Research Group on Diabetes of the Instituto Mexicano del Seguro S
Both drugs can independently cause tachycardia (increased heart rate), and together they may compound this effect, increasing the risk of arrhythmias and other cardiac events