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New England Journal of Medicine, 387(3)
Injections are particularly appropriate for those with: Pernicious anaemia, an autoimmune condition affecting B12 absorption Conditions affecting the stomach or small intestine, such as Crohns disease or coeliac disease Those who have had gastric surgery or bariatric procedures Strict vegans and vegetarians not meeting their B12 needs through food or oral supplements For those who can absorb B12 normally, oral supplements are generally an effective and well-evidenced alternative to injections
However, it's important to note that individual results may vary, and benefits may take several weeks or months to become visible
Once we restore the adequate supply of vitamin B12 in your system, it effectively erases the symptoms mentioned above
This may lead to nutritional deficiencies or malnutrition, so health professionals often check your diet and nutrient intake carefully