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Both carry FDA approval (branded forms) with well-documented adverse event rates
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Functional performance, muscle strength, muscle power, body composition, and waist circumference were evaluated before and after the intervention, and a subset underwent muscle and adipose tissue biopsies to assess mitochondrial and lipid-metabolism markers
For patients with a history of pancreatitis, FDA labeling advises considering other antidiabetic or weight management therapies, though this is not a formal contraindication