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The study shows that of those who discontinued their prescribed injectable semaglutide or tirzepatide for obesity: The study, Reasons for Discontinuation of Obesity Pharmacotherapy With Semaglutide or Tirzepatide in Clinical Practice, was published in the journal Obesity

Compounding pharmacies began offering tirzepatide niacinamide as an alternative when pharmaceutical-grade tirzepatide faced supply shortages and cost barriers

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In a study that examined the effects of GLP-1 receptor agonists (GLP-1 RAs) on liver fibrosis in type 2 diabetes (T2DM) patients with nonalcoholic fatty liver disease (NAFLD)

The researchers speculated that the increased lean body mass was due to more efficient muscle protein synthesis from the less-degraded l-citrulline in the bloodstream

doi: 10.1038/ni.3423