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The catalytic tetrad formed by Sec, glutamine, tryptophan and asparagine is essential for GPx activity, since these residues are crucial for enzyme-substrate interaction and stabilization of the GSH-GPx interaction [47, 65, 66]
doi: 10.1159/000369933 [DOI] [PubMed] [Google Scholar] 83.Esmaeili MH, Enayati M, Khabbaz Abkenar F, Ebrahimian F, Salari AA
Smith PK, Krohn RI, Hermanson GT, Mallia AK, Gartner FH, Provenzano MD, Fujimoto EK, Goeke NM, Olson BJ, Klenk DC: Measurement of protein using bicinchoninic acid
Lancet 372(9652):18091818 Lee SM et al (2012) First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial
H3K27me3 immunohistochemistry was performed in a large series of 122 primary malignant peripheral nerve sheath tumors and 265 melanomas of different variants and stages
GLP-1 receptor agonists have transformed the management of obesity and type 2 diabetes in recent years
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