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The impact has been extraordinary

revenue and Humira the top-selling drug of 2022 which generated 42% of AbbVies total annual U.S

Phase 3 trials are ongoing as of 2026, and the compound is not yet approved for clinical use it remains a research compound in active late-phase development

Excess weight increases the risk of type 2 diabetes, high blood pressure, heart disease, fatty liver disease, sleep apnea, joint pain, stroke, and some cancers

A notable study demonstrated that participants using semaglutide, along with lifestyle interventions like improved diet and exercise, experienced significant weight reduction

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