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Recently, scientists have identified the advanced technology and key pathways, such as nanotechnology drug carriers involving RNA molecular or other mechanisms, such as the leptin-melanocortin and GLP-1/GLP-1R systems that are crucial in energy balance and appetite regulation [80, 81]

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Their effects may be limited to older or overweight people, kidney disease patients, and other groups with carnitine deficiency [82, 83, 84]

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