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doi: 10.2116/analsci.23.517

Together, these advancements in nanocarrier design demonstrate the versatility and clinical potential of polymer- and protein-based delivery systems for GLP-1RAs

Our results showed that 24 hour GHK treatment elevated apoptosis by 1.8 0.17 and 3.3 0.15 fold at 1 and 10 nM, respectively

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This could create different product lanes for oral GLP-1s, high-efficacy injectables, amylin combinations, triple agonists, and maintenance therapies

In conclusion, GLP-1RAs@NPs-WYRGRL significantly enhances the targeting efficiency of drug-loaded nanoparticles to chondrocytes and articular cartilage, prolongs their retention time in cartilage tissue, and thereby reduces excretion through the kidneys