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Exposure to sunlight will indirectly affect the whitening process since it increases the melanin pigments in the skin, thus, might delay the whitening process
turpentine, carrageenin, acetic acid or MgSO 4 writhing (prostaglandin-dependent, prostaglandin-non dependent) tail-pinching tests) along with an antipyretic effect (a decrease of yeast induced fever (4000 mg/kg s.c.))
It's a potent modulator, not a direct activator
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It was also reported that hepatocarcinogenesis was associated with increase of basophilic or amphophilic foci (Goodman et al
