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Consistent with preclinical findings, treatment with a DPP1 inhibitor in a phase 2 study reduced NSP activity and improved outcomes in patients with bronchiectasis

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Its effects include: Reduction in central (abdominal) fat Improved waist-to-hip ratio Lower fat-driven inflammation Reduced fat-storage signaling due to better insulin control This makes it especially relevant for individuals who struggle with stubborn visceral fat despite diet and exercise