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The pretreatment of animals with Ab caused strong decrease in MDA levels in all tissues evaluated, being completely inhibited in the peritoneal cavity, the main focus of bacteria (Figures 5HJ)

The result is greater bioavailability and more reliable clinical response in a convenient, single-dose oral format

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The consequences of these modifications are that IGF-1 LR3 retains the pharmacological activity of IGF-1 as an agonist of the IGF-1 receptor, has very low affinity for the insulin-like growth factor-binding proteins (IGFBPs), and has improved metabolic stability resulting in approximately three times greater potency than IGF-1, with a significantly longer half-life of about 2030 hours relative to IGF-1s half-life of about 1215 hours

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