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Although uncommon, an escitalopram overdose can occur, with consequences ranging from mild to fatal

This is due to the fact that M1 macrophages, which are pro-inflammatory, possess higher concentrations of inducer nitric oxide synthase (iNOS), leading to a greater production of nitric oxide free radicals and stronger protection against lipid peroxidation, when compared to M2 macrophages, which are anti-inflammatory and have lower iNOS concentrations (83)

2020a) but a brief description is given below

Hepatocyte growth factor/scatter factor-induced activation of MEK and PI3K signal pathways contributes to expression of proangiogenic cytokines interleukin-8 and vascular endothelial growth factor in head and neck squamous cell carcinoma

Indeed, it has been found that butylphthalide ameliorates sleep deprivation-induced cognitive decline by reducing the inflammatory response and inhibiting neuronal apoptosis