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The upstream regulation of GPX4 mainly include transcription factors such as Nrf2 (Saxton and Sabatini, 2017

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However, published phase 3 papers focused primarily on total weight and glycemic control without reporting detailed body composition data comparing lean mass preservation between treatment groups

Top methylation foods include chickpeas, pinto beans, lentils, spinach, asparagus, avocado, and beets

It plays key roles in energy metabolism and serves as an essential cofactor for non-redox NAD+-dependent enzymes, including sirtuins, CD38, and poly(ADP-ribose) polymerases

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