A randomized phase III trial evaluated selenium supplementation in selenium-deficient gynecological cancer patients receiving adjuvant radiotherapy, and it proved effective in reducing the incidence of grade 2 diarrhea, particularly in patients with a large planning target volume (387, 388)
Emergence of ePRO libraries of pre-migrated measures ready for deployment helps reduce timelines, but not all vendors build such libraries and most ePRO use of the European Organisation for Research and Treatment of Cancer (EORTC) measures requires study-specific migration
Frontiers in Endocrinology (2023) This comprehensive review looked at 39 different studies to understand how GLP-1 medications and another type of diabetes medication, SGLT2 inhibitors, affect pregnancy and breastfeeding
When semaglutide degrades through deamidation, hydrolysis, or oxidation, the resulting degradation products typically lack the biological activity of the intact molecule
Uncontrolled hypothyroidism may mask how much the GLP-1 medication is actually helping with weight loss, because thyroid-related water retention or metabolic slowdown might offset the drug's effects
B.Al-UbaidiY
