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Circulating inactive platelets move in the proximity of vessel walls (Figure 2A) and rapidly get activated in response to vascular injury

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In view of the blood glucose-raising effect of glucagon, the value of GCGR agonism in these therapies might be questioned

doi: 10.1161/CIRCRESAHA.119.315939 138 ZhangXHouLGuoZWangGXuJZhengZet al

Certain groups need to exercise extreme caution or avoid this combination entirely

This is because GLP-1 agonists may raise the likelihood that certain illnesses will manifest or may worsen current problems