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The Wegovy FDA label carries a clear precaution against use in pregnancy, and animal studies at exposures below the human clinical dose showed embryofetal toxicity including reduced fetal growth and skeletal malformations
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Gelinas R, Mailleux F, Dontaine J, Bultot L, Demeulder B, Ginion A, Daskalopoulos EP, Esfahani H, Dubois-Deruy E, Lauzier B, Gauthier C, Olson AK, Bouchard B, Des Rosiers C, Viollet B, Sakamoto K, Balligand JL, Vanoverschelde JL, Beauloye C, Horman S, Bertrand L (2018) AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation