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Population, Intervention, Comparison, Outcomes and Study (PICOS) design as a framework to formulate eligibility criteria in systematic reviews

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Moreover, all clinical trials are evolving, presenting progressively more complex designs, and this also renders first-in-human clinical trial design more complex and challenging

doi:10.1155/2015/648108 Philp D, Goldstein AL, Kleinman HK

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BPC-157, whose full name is Body Protection Compound-157, is a synthetic peptide with the amino acid sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val