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Circ Res 2006
This is an important vitamin for immune system function
however, they do not contain adequate amounts to be used as the sole dietary source
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However, it is crucial to note that it should not be used in patients with a known allergy to cobalamin or cobalt
Multi-dose vials: Each needle puncture creates potential entry point for contaminants After 10-15 punctures, seal integrity weakens Recommendation: Use vial within 28 days even if seal appears intact Single-dose draws: If drawing entire vial in one session, seal integrity not an issue Can preload syringes for convenience (store in fridge, use within week) Extending shelf life: tips and tricks While 28-30 days is standard, these practices maximize longevity
