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Further, DUSP4 regulates ferroptosis by regulating FTL expression

Bikdeli B, Madhavan MV, Jimenez D, Chuich T, Dreyfus I, Driggin E, Der Nigoghossian C, Ageno W, Madjid M, Guo Y, Tang LV, Hu Y, Giri J, Cushman M, Qur I, Dimakakos EP, Gibson CM, Lippi G, Favaloro EJ, Fareed J, Caprini JA, Tafur AJ, Burton JR, Francese DP, Wang EY, Falanga A, McLintock C, Hunt BJ, Spyropoulos AC, Barnes GD, Eikelboom JW, Weinberg I, Schulman S, Carrier M, Piazza G, Beckman JA, Steg PG, Stone GW, Rosenkranz S, Goldhaber SZ, Parikh SA, Monreal M, Krumholz HM , Konstantinides SV, Weitz JI, Lip GYH, Global COVID-19 Thrombosis Collaborative Group E

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Two additional enzymes of folate metabolism, aldehyde dehydrogenase 1 family member L1 (encoded by the ALDH1L1 gene) and ALDH1L2, produce NADPH in the course of converting N 10 -formyltetrahydrofolate (10-formyl-THF) to tetrahydrofolate (THF) and CO 2

doi: 10.1016/S2213-2600(20)30161-2 219 PoeF

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