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Table of Several Gut Microbiota Metabolites Involved in Host Homeostasis Gut Bacteria: Roles in Metabolism, Obesity, and Immunity Given that obesity, insulin resistance, and type 2 diabetes are all associated with low-grade systemic inflammation of unclear etiology, it has been proposed that one mechanism leading to this state involves inflammatory modulation by gut bacteria

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PMID 15610346

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Clinicians should carefully assess all nails for atypical features that may indicate a developing periungual melanoma and prompting a referral to a dermatologist for evaluation (Box 7-1)