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Bariatric surgery in proper candidates can be effective and safe for improving steatosis, inflammation and to a lesser degree liver fibrosis and must be carefully evaluated in individuals with cirrhosis [33, 34]

This point matters because it shifts the conversation away from appearance and toward long-term health outcomes such as heart attack and stroke risk

These findings suggest that coordinated incretin and glucagon receptor activation may influence pathways involved in hepatic lipid handling and metabolic signaling [5][8]

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The drug received approval from both the US FDA and the European Union in 2022 for the treatment of type 2 diabetes, demonstrating signicant glucose-lowering and weight-loss efects in multiple clinical trials

The region accounts for roughly two-fifths of the worlds overweight or obese adults, totaling about 1 billion people