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Various transcription factors are responsible for controlling cell differentiation

Despite usually being a lifelong condition, hypothyroidism can be managed effectively for a healthy life and, in some cases, reversed entirely

Glucuronidation: UGTs catalyze an SN2 nucleophilic substitution where the substrate's nucleophilic functional group (OH, NH2, SH, COOH) attacks the C1 carbon of glucuronic acid in UDPGA, displacing UDP

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AICAR has been suggested to exert this potential

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