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Athough increase in liver size as measured by liver weight is correlated with microsomal enzyme induction, neither the degree or extent of hypertrophy nor the magnitude of the weight increase is correlated with the magnitude of the enzyme induction in rats, dogs, or monkeys (Amacher et al

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These approaches could maximize the benefits of dual agonism while personalizing treatment to individual patient needs

A: They are different tools

Interactions with immune checkpoint inhibitors and targeted therapies remain incompletely characterized, underscoring the need for pharmacovigilance and individualized risk assessment

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