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At the conclusion of the study, the once-weekly exenatide-treated group exhibited significantly reduced HbA1c level (about 1.5%) ( P =0.017) compared with the insulin glargine-treated group (1.3%)80)

You should not take semaglutide or tirzepatide if you have: Personal or family history of medullary thyroid carcinoma Multiple endocrine neoplasia syndrome type 2 (MEN2) History of pancreatitis or gallbladder disease Severe kidney or liver disease Diabetic retinopathy (in some cases) Severe gastrointestinal disease Pregnancy or breastfeeding This is not a complete list of contraindications

Some experience mild nausea or headaches early on, but these usually fade quickly

When acid reaches the throat, it can irritate and inflame the vocal cords, which may affect the voice. Importantly, Jelly Roll has been clear that his choice isnt a judgment on anyone elses