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ROS and oxidatively modified macromolecules function as damage-associated molecular patterns (DAMPs), engaging pattern recognition receptors (PRRs) on microglia, including Toll-like receptors (TLRs) and NOD-like receptors (NLRs), to initiate inflammatory cascades ( Microglia, the resident immune cells of the CNS, are tightly regulated under physiological conditions to maintain neural homeostasis

Mild fatigue may occur

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5, May 2013, pp

CTRP5 promotes transcytosis and oxidative modification of low-density lipoprotein and the development of atherosclerosis

The drug was easy to get: In drug stores, it could be purchased in unlimited quantities