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Methods SpragueDawley rats were randomly divided into five groups: control (saline with the same volume), BPC10 (10 g/kg of BPC-157), BPC20 (20 g/kg of BPC-157), BPC40 (40 g/kg of BPC-157), and morphine (5 mg/kg of morphine)

Each step often requires flow sorting, drug selection and often clone screening, resulting in weeks to months per allele of interest

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In the REDEFINE 1 trial, 79.6% of combination participants experienced GI events versus 39.9% on placebo

A SALT score of 7.5% is barely noticeable