Important safety considerations include caution in patients with diabetic retinopathy, particularly with semaglutide, as rapid improvement in glucose control may temporarily worsen retinopathy
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Anxiety and GLP-1 Use: What Clinical Evidence Shows Large-scale trials of semaglutide, including the SUSTAIN and STEP series, monitored mood and psychiatric adverse events as secondary outcomes
In that context, a metabolic support probiotic is best understood as a microbiome-supportive option that may complement barrier regulation and microbial metabolite pathways, not as a stand-alone solution for intestinal permeability
And I think we should be open to the idea that some of these peptides could have important clinical uses in people