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A 2024 study in monkeys found metformin reversed molecular aging markers (e.g., reduced inflammation, improved DNA repair) in multiple organs, effectively making their tissues 6 years younger. Lifespan : The evidence is mixed: In mice, metformin extended lifespan by 14% when started young, but had minimal effects in older mice, a 2013 study found

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Semaglutide , Tirzepatide , and other medical peptides mimic natural hormones that regulate hunger, metabolism, and blood sugar