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Inhibiting core enzymes of DNL, including citrate/isocitrate carrier (CIC), ATP-citrate lyase (ACLY), acetyl-CoA carboxylase (ACC) and fatty acid synthase (FAS), represents an attractive therapeutic strategy

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Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid

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Limitations and future studies We used an in vitro monolayer of neurons to model metabolism dysfunction, which may not reflect the complexity of extracellular matrices in an in vivo environment