Drug analogues are compounds that are similar to the parent drug but are chemically modified to enhance certain characteristics while retaining its biological activity [19,20]
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This shows that the use of unnatural stereochemistry in GSH is unlikely to prevent the substantial first-pass metabolism by GGT in the liver for orally administered GSH, and it is also unlikely to aid in improving its oral bioavailability [31]
Chem Biol Drug Des 87:374381 Dennison SR, Harris F, Phoenix DA (2007) The interactions of aurein 1.2 with cancer cell membranes
Over 40 peptides have received approval for clinical use, reflecting serious clinical adoption in medicine and performance optimization
