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Toda T, Hsu JY, Linker SB, Hu L, Schafer ST, Mertens J, et al

Obesity Treatment With Bariatric Surgery vs GLP-1 Receptor Agonists How do bariatric surgery (sleeve and gastric bypass) and glucagon-like peptide-1 receptor agonists (#GLP1s - dulaglutide, exenatide, liraglutide, lixisenatide, #semaglutide, or #tirzepatide) compare as #obesity treatments regarding weight loss, ongoing costs, and health care utilization in a clinical setting

That is a prescriber decision

Typically those with MTHFR polymorphisms (C677T or A1298C variants reduce methylenetetrahydrofolate reductase activity by 3070%), chronic alcohol use (depletes SAMe and impairs methionine adenosyltransferase), or vegan diets without B12 supplementation

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For pets needing additional cardiovascular support, Rooted Owl Cardio Support provides L-Carnitine (200mg) and L-Taurine (200mg)two key compounds that promote heart muscle function, circulation, and normal blood pressure