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This section summarizes current research progress on mitochondrial biogenesis, mitophagy, and mitochondrial dynamics in common neurodegenerative diseases (AD, PD, HD, and ALS) (Figure 5)

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Lipid metabolism disorders play a crucial role, with numerous studies confirming alterations in lipid composition in the plasma and brain of patients with AS and depression

This can happen in malabsorption syndromes, chronic alcoholism, and some neurological issues

Moreover, glutaminolysis critically contributes to maintaining redox homeostasis by promoting GSH synthesis and elevating NADPH levels [37]