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The primary purpose of Wegovy is chronic weight management in adults with obesity or overweight with at least one weight-related comorbidity

The reduction in both the diversity and abundance of gut microbiota compromises microbial defense mechanisms, facilitating pathogenic bacteria invasion of the intestinal mucosa, breaching the intestinal barrier, and triggering immune dysregulation that promotes the development of colitis[72], [73]

Journal of Pharmacy & Bioallied Sciences

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Asking tough questions and seeking clear regulatory guidance isn't being resistant to change, it's part of protecting patients and maintaining the integrity of the profession.