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In particular, two short-acting formulations of Lixisenatide and Exenatide and four long acting preparations of Exenatide, Liraglutide, Dulaglutide and the most recent and successful Semaglutide, were approved in October, 2017 for the North American markets by FDA 1 (185)

5 In 2021, there were 529 million people of all ages in worldwide living with diabetes, and the global age-standardized prevalence is 6.1%, which increased by 90.5% from 3.2% in 1990, and is expected to reach 9.8%, affecting 13.1 billion people

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Expert Opinion GLP-1 receptor agonists, along with dual and triple agonists, have transformed the landscape of adolescent obesity treatment, offering an effective alternative to lifestyle interventions that often fail to produce long-term results