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Who Should Use GLP-1 Supplements: Eligibility and Safety Considerations GLP-1 supplementation is most appropriate for adults with BMI 27 kg/m (with weight-related comorbidity) or BMI 30 kg/m without comorbidity, or those with type 2 diabetes

The infusion of glucose in ewes during the luteal phase increases the number of follicles but reduces oestradiol production and some correlates of metabolic function in the large follicles

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16 Other less common potential adverse effects include gallbladder disease, pancreatitis and pancreatic cancer, thyroid cancer, acute kidney injury, and worsening of diabetic retinopathy (DRP)

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2024 NEJM) showed 24% reduction in kidney disease progression on semaglutide for type 2 diabetes with CKD