Effects of Low-Dose, Controlled-Release, Phentermine Plus Topiramate Combination on Weight and Associated Comorbidities in Overweight and Obese Adults (CONQUER): A Randomised, Placebo-Controlled, Phase 3 Trial (April 16, 2011) TOPAMAX (topiramate) TABLETS, for oral use product label (1996) Topiramate (Topamax): Evolving Role in Weight Reduction Management: A Narrative Review (August 31, 2023) Efficacy and Safety of Topiramate in Binge Eating Disorder: A Systematic Review and Meta-analysis (July 9, 2020) Brief Communication: Sleep Curtailment in Healthy Young Men Is Associated with Decreased Leptin Levels, Elevated Ghrelin Levels, and Increased Hunger and Appetite (December 7, 2004) Effects of Chronic Social Stress on Obesity (January 11, 2012) Physical Activity/Exercise and Diabetes: A Position Statement of the American Diabetes Association (October 11, 2016) Severity of Topiramate-Related Working Memory Impairment Is Modulated by Plasma Concentration and Working Memory Capacity (April 16, 2020) Clinical Utility Of Phentermine/Topiramate (Qsymia) Combination For The Treatment Of Obesity (April 08, 2013) Once-Weekly Semaglutide in Adults With Overweight or Obesity (February 10, 2021) Tirzepatide Once Weekly for the Treatment of Obesity (June 4, 2022) OZEMPIC (semaglutide) injection, for subcutaneous use
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Liraglutide, a GLP-1 receptor agonist, improves weight and glycaemic control in patients with T2DM
In atherosclerosis, GPER promotes smooth muscle cell proliferation and migration via the PI3K/AKT pathway [197, 198] and reduces oxidative stress by downregulating Nox1 expression, thereby decreasing reactive oxygen species production [199]
Long-term use of these drugs may increase the risk of gastrointestinal issues
Revealing the role of glutathione S-transferase omega in age-at-onset of Alzheimer and Parkinson diseases
