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Patients who started GLP-1s shortly after diagnosis had higher metformin use and fewer fertility procedures

A continuous infusion of IV N-acetylcysteine was commenced to replenish hepatic glutathione stores and boluses of sodium bicarbonate were given initially to normalize the pH

SCFAs exert a substantial regulatory influence on both body weight and bone health (113)

In the liver, kidneys, pancreas, and bile ducts, GGT breaks GSH into amino acids for resynthesis and energy production

Preclinical studies further suggest that GLP-1RAs may modulate key cytokine pathways implicated in psoriatic disease, including NF-B, IL-6, IL17, and IL23, while small clinical studies have reported improvements in skin disease severity in PsO (37)