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doi: 10.1136/gutjnl-2014-307264

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the higher oxygen affinity of HbF, even in the presence of 2,3-BPG, promotes efficient transfer of O 2 across the placenta from HbA to HbF (see Chapter 5 )

The same results were observed in a small study in older humans who had high oxidative stress and glutathione deficiency inside cells