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Results of a comparative trial of amsacrine/cytarabine/thioguanine (AAT) and daunorubicin /cytarabine /thioguanine (DAT) in patients with untreated acute non lymphocytic leukemia (ANLL): Results of the L 16M protocol

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This special interplay further highlights that the loss of any one system can overwhelm the compensatory capacity of the others, forcing the CNS into a state of redox imbalance, glial activation, and progressive inflammation (Figure 1)

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Our discussion so far has focused on the cellular LIP, but 95% of functional iron in the body is in heme