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aureus is the second leading pathogen for human deaths associated with antibiotic resistance, and MRSA caused more than 100,000 deaths worldwide in 2019 [15], which urgently claims a new drug or strategy to treat MRSA

Arginase acts on L-arginine, yielding ornithine, which is decarboxylated by ornithine decarboxylase to form putrescine (MacMicking et al., 1997)

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