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Author contributions YuZ and XQ designed the study

Over the last 5 years, with the emergence of newer agents including sodium-glucose cotransporter-2 (SGLT2) inhibitors, glucagon-like peptide-1 receptor agonists (GLP-1 RA) and novel mineralocorticoid receptor antagonist (MRA), management of type 2 diabetes mellitus (T2DM) and DKD has since shifted away from a glucose-centric focus towards one of heart and kidney protection [35]

Verify that HPLC purity exceeds 95% at minimum, with 98% or higher being preferred for receptor binding studies

glabra and has pharmacological activities, including anti-oxidant, anti-inflammatory, and anti-cancer (Finney and Somers, 1958

The real difference between the two ingredients becomes apparent when you begin administering them

Tissue inflammation and chronic infection lead to the overproduction of O 2 and NO , which rapidly combine to yield peroxynitrite: O 2 + NO ONO 2