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Hypertension induced by chemotherapeutic and immunosuppresive agents: a new challenge

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2011;92(1):e78

[81] Transglutaminase substrates: Amyloid-beta, tau, alpha-synuclein and huntingtin have been proved to be substrates of transglutaminases in vitro or in vivo, that is, they can be bonded by trasglutaminases by covalent bonds to each other and potentially to any other transglutaminase substrate in the brain

First, these results were obtained in controlled clinical trial conditions with carefully selected participants