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20 Similarly, A phase 2 trial of 320 patients with biopsy-confirmed MASH found that daily subcutaneous semaglutide (0.4 mg) achieved steatohepatitis resolution without fibrosis progression in 59% of patients vs

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SURMOUNT-1 (N=2,539) showed 20.9% mean weight loss at 72 weeks with tirzepatide 15 mg versus 3.1% with placebo

This animal model also enabled histological examinations of the treated tissue

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