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A livello gastrointestinale rallenta lo svuotamento dello stomaco, contribuendo alla riduzione dei picchi postprandiali

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However, the results of A Long Term Evaluation (LEADER) trial that followed for 3.5-5 years showed no effect of GLP-1 receptor activation on human serum calcitonin levels, C-cell proliferation or C-cell malignancy (15)

Other meta-analyses have made stronger claims

Does Rybelsus increase heart rate

Individuals with specific genetic variantssuch as GIPR rs1800437 or MC4R rs17782313may show enhanced response to tirzepatide's dual action